The detection of genetically linked cVDPV2 in wastewater across multiple European countries suggests a broader geographic distribution of the virus.
Alerts clinicians to possible silent cVDPV2 circulation; leaves open extent of cross-border transmission.
In 2024, circulating vaccine-derived poliovirus type 2 (cVDPV2) was detected in wastewater samples in Finland, Germany, Poland, Spain and the United Kingdom (UK). All strains were genetically linked, but sequence analysis showed high genetic diversity among the strains identified within individual wastewater sites and countries and an unexpected high genetic proximity among isolates from different countries. Taken together these results, with sequential samples having tested positive in various sites, a broader geographic distribution beyond positive sampling sites must be considered.
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Böttcher et al. (2025) studied this question.
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