June 11, 2008The American Journal of Sports Medicine196 citations

Angiotensin II Receptor Blockade Administered after Injury Improves Muscle Regeneration and Decreases Fibrosis in Normal Skeletal Muscle

HBHany S. BedairNorthwestern University TKTharun KarthikeyanUniversity of Pittsburgh Medical Center AQAndres QuinteroPfizer (United States)

Structured PICO

Does Angiotensin II Receptor Blockade improve muscle regeneration and decrease fibrosis in normal skeletal muscle after injury?

Population

Normal skeletal muscle with injury

Intervention

Angiotensin II Receptor Blockade (Angiotensin receptor blockers) administered after injury

Outcome

Muscle regeneration and fibrosissurrogate

Angiotensin receptor blockers may offer a clinically available pharmacological strategy to enhance healing and reduce fibrosis following skeletal muscle injury.

Abstract

Angiotensin receptor blockers may provide a safe, clinically available treatment for improving healing after skeletal muscle injury.

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Cite This Study

Bedair et al. (Wed,) studied this question.

synapsesocial.com/papers/69da28bea6045d71bfa3c4fd https://doi.org/https://doi.org/10.1177/0363546508315470

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