Why the study?
Does ACE genotype affect changes in strength of quadriceps muscles in response to 9 weeks of specific strength training in healthy male volunteers?
Population
33 healthy male volunteers with no experience of strength training
Comparison
9 weeks of specific strength training vs Comparison across ACE genotypes (II, ID, DD)
Design
Cohort
Follow-up
9 weeks
Authors
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D allele carriers may experience greater strength gains from training; leaves open clinical utility of ACE genotyping in exercise prescription.
Does ACE genotype affect changes in strength of quadriceps muscles in response to 9 weeks of specific strength training in healthy male volunteers?
The ACE D allele is associated with significantly greater skeletal muscle strength gains in response to functional overload compared to the II genotype.
Folland et al. (2000) studied this question.
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