Key result
ACE ID genotype explained approximately 1% of the MVC response to resistance training in the trained arm and 2-4% of strength and size responses in the untrained arm (P<0.05).
Why the study?
Does ACE ID genotype affect muscle strength and size response to unilateral resistance training in adults?
Population
631 adults (mean age 24.2+/-0.2 yr, 80% white, 42% men, 58% women)
Comparison
12-wk unilateral, upper-arm resistance training… vs Untrained arm and comparison across ACE ID…
Design
Cohort
Follow-up
12 weeks
Authors
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Modest ACE ID links to contralateral adaptations do not support genotyping; leaves open genetic roles in cross-education responses.
Observational (n=631)
Does ACE ID genotype affect muscle strength and size response to unilateral resistance training in adults?
p-value: p=<0.05
ACE ID genotype is associated with the contralateral effects of unilateral resistance training, with modest effects on muscle strength adaptations.
Pescatello et al. (2006) conducted an observational in Healthy volunteers (n=631). Unilateral upper-arm resistance training (ACE ID genotype association) vs. Untrained arm and different ACE ID genotypes was evaluated on Maximum voluntary contraction (MVC), one-repetition maximum (1RM), and biceps muscle cross-sectional area (CSA) (p=<0.05). ACE ID genotype explained approximately 1% of the MVC response to resistance training in the trained arm and 2-4% of strength and size responses in the untrained arm (P<0.05).
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