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April 16, 2013The American Journal of Gastroenterology191 citations

Mucosal Cytokine Response After Short-Term Gluten Challenge in Celiac Disease and Non-Celiac Gluten Sensitivity

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MBMargit BrottveitABAnn-Christin Røberg BeitnesSTStig Tollefsen

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Abstract

CD patients mounted a concomitant innate and adaptive immune response to gluten challenge. NCGS patients had increased density of intraepithelial CD3(+) T cells before challenge compared with disease controls and increased IFN-γ mRNA after challenge. Our results warrant further search for the pathogenic mechanisms for NCGS.

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Brottveit et al. (2013) studied this question.

synapsesocial.com/papers/69da6e5b8988aeabbe686cb0https://doi.org/10.1038/ajg.2013.91
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