Longitudinal Analysis of Multiple Neurotransmitter Metabolites in Cerebrospinal Fluid in Early Parkinson's Disease

Thomas Kremer; Kirsten I. Taylor; Juliane Siebourg‐Polster; Thomas Gerken; Andreas Staempfli; Christian Czech; Juergen Dukart; Douglas Galasko; Tatiana Foroud; Lana M. Chahine; Christopher S. Coffey; Tanya Simuni; Daniel Weintraub; John Seibyl; Kathleen L. Poston; Arthur W. Toga; Caroline M. Tanner; Kenneth Marek; Samantha J. Hutten; Sebastian Dziadek; Claudia Trenkwalder; Gennaro Pagano; Brit Mollenhauer

doi:10.1002/mds.28608

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HVA and DOPAC CSF levels mirrored nigrostriatal pathway damage, confirming the central role of dopaminergic degeneration in early PD. © 2021 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

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Kremer et al. (2021) studied this question.

synapsesocial.com/papers/69da8c41a6045d71bfa3d020 https://doi.org/10.1002/mds.28608

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Longitudinal Analysis of Multiple Neurotransmitter Metabolites in Cerebrospinal Fluid in Early Parkinson's Disease

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Longitudinal Analysis of Multiple Neurotransmitter Metabolites in Cerebrospinal Fluid in Early Parkinson's Disease

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