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September 1, 2000Annual Review of Genomics and Human GeneticsOpen Access

Apolipoprotein E: Far More Than a Lipid Transport Protein

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Authors

Robert W. Mahley
Robert W. MahleyPreventive CardiologySRStanley C. RallGladstone Institutes

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Mahley et al. (2000) studied this question.

synapsesocial.com/papers/69da924a615cc0c8eaa3bfb4https://doi.org/10.1146/annurev.genom.1.1.507
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Expression of apolipoprotein E by cultured vascular smooth muscle cells is controlled by growth state.1988 · 61 citations
  2. 2Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology1988 · 4,055 citations
  3. 3A Minimally Lipidated Form of Cell-derived Apolipoprotein E Exhibits Isoform-specific Stimulation of Neurite Outgrowth in the Absence of Exogenous Lipids or Lipoproteins1998 · 127 citations
  4. 4Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line.1995 · 351 citations
  5. 5Susceptibility to diet-induced atherosclerosis in transgenic mice expressing a dysfunctional human apolipoprotein E(Arg 112,Cys142).1994 · 47 citations