2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

Key Points

To establish evidence-based clinical practice recommendations for healthcare professionals managing patients during the initial presentation and early hospital phase of acute ischemic stroke.
Expert consensus panel evaluated published randomized clinical trials and observational studies on acute ischemic stroke care.
Evidence categorized and graded according to standard American Heart Association and American Stroke Association guideline methodology.
Recommends rapid emergency assessment and administration of intravenous alteplase within eligible time windows to restore cerebral perfusion.
Endorses mechanical thrombectomy for eligible patients with acute large vessel occlusions in the anterior circulation within designated treatment windows.

Clinical practice guideline outlines evidence-based protocols for acute ischemic stroke, highlighting emergency evaluation and reperfusion therapies.

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Powers et al. (2018) studied this question.

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