The study demonstrates that aortic stenosis shows accelerated gradient progression over time, but prognosis remains comparable to the normal population during the asymptomatic phase and post-surgery.
Supports conservative management in asymptomatic aortic stenosis and post-surgery; leaves open drivers of accelerated progression in observational cohorts.
This is the first study to document the incidence and prognosis of AS in a general population with surgery as a treatment option. It reveals an accelerated progression of the aortic mean gradient as the disease advances. The prognosis of AS seems to be comparable with the normal population in the asymptomatic stage and after successful surgery, indicating that the follow-up and timing of surgery has been adequate for this patient group.
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Eveborn et al. (2012) studied this question.
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