Why the study?
Does electrical stimulation of the periventricular/periaqueductal grey matter regulate arterial blood pressure in awake humans?
Population
15 awake human study participants following implantation of deep brain stimulating electrodes for treatment…
Comparison
Electrical stimulation of the… vs Comparison between ventral and dorsal…
Design
Case_series
Authors
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Hypothesis-generating for site-specific PAG stimulation to modulate BP; prospective trials needed before any clinical consideration.
Does electrical stimulation of the periventricular/periaqueductal grey matter regulate arterial blood pressure in awake humans?
Deep brain stimulation of specific regions of the periaqueductal grey matter can directly modulate arterial blood pressure in awake humans, extending findings from animal models.
Green et al. (2005) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: