Answers are grounded in this paper and cite their sources.
Treatment of tertiary homopropargyl alcohol with aryl halide under palladium catalysis provided arylallenes regioselectively. The reaction includes retro-propargylation, which proceeds in a concerted fashion via a cyclic transition state and transfers the stereochemistry of homopropargyl alcohols through C-C bond cleavage. The present method enables the use of homopropargyl alcohols as allenylmetal equivalents.
No takes yet. Share an insight, caveat, or question.
Hayashi et al. (2008) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: