What question did this study set out to answer?

To develop and evaluate a random-access optical-resolution photoacoustic microscopy system that selectively scans arbitrary regions of interest at high speeds.

July 19, 2013Optics Letters

Random-access optical-resolution photoacoustic microscopy using a digital micromirror device

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Authors

JLJinyang LiangInstitut National de la Recherche Scientifique YZYong ZhouShanghai Jiao Tong University AWAmy W. WinklerWashington University in St. Louis

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Implication

Preclinical imaging study demonstrates targeted capillary blood flow tracking in mouse ears, indicating enhanced imaging speeds through selective scanning.

Key Points

To develop and evaluate a random-access optical-resolution photoacoustic microscopy system that selectively scans arbitrary regions of interest at high speeds.
Engineered an optical-resolution photoacoustic microscopy system using a digital micromirror device providing a 40 μm × 40 μm scanning area and 3.6 μm lateral resolution.
Bench-tested random-access capability on static targets, including a carbon fiber cross and a red blood cell monolayer.
Monitored in vivo capillary blood flow in real time within selected microvessels in a mouse ear model.
Demonstrated static random-access target imaging at an acquisition rate of up to 4 kHz.
Accelerated the real-time in vivo frame rate by up to 9.2 times by scanning only the targeted microvessel rather than the entire field.

Cite This Study

Liang et al. (2013) studied this question.

synapsesocial.com/papers/69dabfacaae38ff6ad8366ec https://doi.org/10.1364/ol.38.002683

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Implication

Preclinical imaging study demonstrates targeted capillary blood flow tracking in mouse ears, indicating enhanced imaging speeds through selective scanning.

Random-access optical-resolution photoacoustic microscopy using a digital micromirror device

Discussion

Member takes

Implication

Key Points

Cite This Study

Random-access optical-resolution photoacoustic microscopy using a digital micromirror device

Discussion

Member takes

Implication

Key Points

Cite This Study

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