Does a strategy of PCI with sirolimus-eluting balloon and provisional DES reduce target vessel failure compared to systematic DES in all-comers with de novo coronary lesions?
The SELUTION DeNovo trial will determine if a sirolimus-eluting balloon strategy with provisional stenting is non-inferior to systematic drug-eluting stenting in all-comers with de novo coronary lesions.
SELUTION DeNovo trial is an open-label, multi-center international randomized trial comparing a strategy of PCI with SEB and provisional DES to a strategy of PCI with systematic DES on TVF at one and five years. Non-inferiority will be tested at one and five years. If non-inferiority is met at five years, superiority will be tested.
Spaulding et al. (Fri,) studied this question.