What question did this study set out to answer?

To establish an efficient and simplified recipient preparation protocol for mouse embryo transfer using hormone-induced estrous synchronization and mating with fertile males.

December 31, 2021Journal of Animal Reproduciton and BiotechnologyOpen Access

Hormone induced recipients for embryo transfer in mice

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Authors

YLYeonmi LeeCHA Bundang Medical Center EKEunju KangSejong University

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Implication

Comparative study shows hormone synchronization and natural mating improve embryo transfer in mice, indicating a simpler alternative to vasectomy.

Key Points

To establish an efficient and simplified recipient preparation protocol for mouse embryo transfer using hormone-induced estrous synchronization and mating with fertile males.
Evaluated a recipient preparation protocol combining hormone-induced estrous cycle synchronization and natural mating with intact wild male mice.
Compared delivery rates and birth outcomes of transferred embryos against conventional pseudopregnant recipients selected at the proestrus stage and mated with surgically vasectomized males.
Delivery rates in recipient mice reached 100% with hormone-induced estrous synchronization compared to 71% with the conventional method.
Birth rates of transferred offspring were significantly higher in recipients undergoing natural pregnancy via intact males compared to the conventional protocol (33% vs. 13%).

Cite This Study

Lee et al. (2021) studied this question.

synapsesocial.com/papers/69db1d23498b35d3e6a3c606 https://doi.org/10.12750/jarb.36.4.247

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Implication

Comparative study shows hormone synchronization and natural mating improve embryo transfer in mice, indicating a simpler alternative to vasectomy.

Hormone induced recipients for embryo transfer in mice

Discussion

Member takes

Implication

Key Points

Cite This Study

Hormone induced recipients for embryo transfer in mice

Discussion

Member takes

Implication

Key Points

Cite This Study

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