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April 12, 2026Frontiers in Dental MedicineOpen Access

Evaluation of the effect of two biomimetic approaches on micro-tensile bond strength of one etch & rinse adhesive to dentin (An in vitro study)

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Authors

ASAhmad Diaa El Din Abou El SeoudENessam Abdel Hafez NaguibEAEman Ali Abou Auf

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Overview

In vitro evaluation shows enhanced bond strength using self-assembling peptide in dentin, implying improved adhesive durability.

Key Points

  • This study evaluates the efficacy of two biomimetic approaches on bond strength between an adhesive and dentin.
  • Fifty-four extracted human molars were demineralized and assigned to three treatment groups: control, self-assembling peptide P11-4, and PILP.
  • Each group was subdivided by storage time (24 h, 3 days, 14 days).
  • Micro-tensile bond strength (µTBS) was assessed using a universal testing machine.
  • P11-4 showed the highest mean µTBS values at initial time points compared to other groups.
  • At longer storage times, the control group exhibited better µTBS than both biomimetic groups.
  • Failure analysis indicated mixed failures at early periods, transitioning to adhesive failures in biomimetic groups over time.

Cite This Study

Seoud et al. (2026) studied this question.

synapsesocial.com/papers/69db35be4fe01fead37c44behttps://doi.org/10.3389/fdmed.2026.1791403
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