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To report a unique case of hypereosinophilic syndrome associated with ischemic stroke due to intracranial artery stenosis.

Hypereosinophilic syndrome with central nervous system involvement: a case report

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To report a unique case of hypereosinophilic syndrome associated with ischemic stroke due to intracranial artery stenosis.
Case report of a patient with hypereosinophilic syndrome and acute ischemic stroke.
Diagnosis was confirmed through bone marrow aspiration showing eosinophilia and negative genetic tests.
Treatment included intravenous thrombolysis with alteplase and subsequent immunosuppressive therapy.
High-resolution magnetic resonance imaging was used to assess artery conditions.
The patient's NIH Stroke Scale score improved significantly from 13 to 2 post-treatment.
High-resolution MRI indicated inflammatory processes in the affected arteries with significant changes after 17 months of therapy.
Eosinophil count remained stable during the two-year follow-up with no recorded stroke recurrence.

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A case report reveals ischemic stroke in a hypereosinophilic syndrome patient, suggesting rare complications with treatment outcomes.

Xu et al. (2026) studied this question.

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