What question did this study set out to answer?

This research aims to compare the effects of plant-based enteral nutrition and ultra-processed formulas on recovery from antibiotic-induced dysbiosis.

April 12, 2026JCI InsightOpen Access

Plant-based enteral nutrition outperforms ultra-processed formulas in mitigating consequences of antibiotic-induced dysbiosis

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This research aims to compare the effects of plant-based enteral nutrition and ultra-processed formulas on recovery from antibiotic-induced dysbiosis.
Conducted a pilot clinical study and mouse models
Compared plant-based enteral nutrition (PBEN) and artificial enteral nutrition (AEN)
Assessed gut microbiome composition and clinical outcomes
Measured blood cell counts and lymphocyte populations in subjects
PBEN showed superior restoration of the gut microbiome compared to AEN
Subjects on PBEN had reduced anemia and leukopenia
Restored naïve lymphocyte populations observed in PBEN group
PBEN led to improved responses to infections post-antibiotic exposure

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Implication

Pilot study shows plant-based nutrition improves recovery from dysbiosis in critically ill children, suggesting better clinical outcomes.

Cite This Study

Chatrizeh et al. (2026) studied this question.

synapsesocial.com/papers/69db36a04fe01fead37c49a5 https://doi.org/10.1172/jci.insight.199827

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Plant-based enteral nutrition outperforms ultra-processed formulas in mitigating consequences of antibiotic-induced dysbiosis

Key Points

Discussion

Implication

Cite This Study

Plant-based enteral nutrition outperforms ultra-processed formulas in mitigating consequences of antibiotic-induced dysbiosis

Key Points

Discussion

Implication

Cite This Study

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