Case report demonstrates effectiveness and tolerability of massed prolonged exposure therapy for PTSD in Veterans, suggesting potential innovation in treatment.
Posttraumatic stress disorder (PTSD) is associated with significant distress, impairment, and societal cost. Prolonged exposure therapy (PE) is a gold standard psychotherapy that has been validated for military/Veteran populations, has practical and clinical barriers, and has a moderate drop-out rate, in spite of its efficacy. Standard PE (SPE) involves 12-15 weekly sessions, while massed PE (MPE) involves daily sessions, typically offered over a two-week period. This case report examined the effectiveness and tolerability of MPE in a treatment-seeking Veteran. Baseline structured clinical interview and self-report questionnaire data were compared with post-treatment and follow-up data, with the primary outcome measure being the change in PTSD symptom severity on a structured clinical interview. MPE resulted in reduced PTSD and associated symptom severity as measured at the end of treatment and at follow-up. MPE was described as tolerable, despite short-term discomfort associated with the intense format, and beneficial in facilitating efficient and effective clinical change. This case report demonstrated the effectiveness and tolerability of MPE in a treatment-seeking Veteran. It raises attention for clinical innovation in evidence-based practice and encouragement for empirical replication of this finding in a larger, representative sample.
No takes yet. Share an insight, caveat, or question.
Maya Roth (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: