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April 12, 2026CureusOpen Access

Restructuring the Obesity Paradigm: Molecular Etiologies, Clinical Complexities, and the Future of Precision Intervention

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Authors

TLTint S LattTAThan T AyeKKKo Oo Htet Ko

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Overview

This review highlights molecular causes and future treatment strategies for obesity, suggesting a shift to holistic care models.

Key Points

  • To review the complex etiology of obesity and highlight emerging treatment options and care strategies.
  • Consolidated evidence on obesity's pathophysiology and genetic factors
  • Reviewed hormonal and microbiome influences
  • Discussed interventions including glucagon-like peptide-1 therapies and surgical options
  • Evaluated impact of AI and precision medicine on treatment
  • Assessed barriers to care in high-income and low-resource settings.
  • Obesity is a multifactorial condition linked to various genetic, hormonal, and environmental factors.
  • Emerging therapies show promise but remain underutilized due to healthcare system limitations.
  • Artificial intelligence is changing how personalized obesity treatment is approached.
  • High costs and fragmented care hinder access to advanced therapies globally.

Cite This Study

Latt et al. (2026) studied this question.

synapsesocial.com/papers/69db38274fe01fead37c64dbhttps://doi.org/10.7759/cureus.106767
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Also Consider

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  3. 3Understanding Obesity as a Multisystem Disease: Advancing Research, Redefining Diagnostic Criteria, and Establishing Modern Therapeutic Approaches2026 · 1 citations
  4. 4Obesity – Standards, trends and advances2024 · 12 citations
  5. 5Biotechnology and Bioengineering Innovations in Precision Obesity Management: Mechanistic Insights, Emerging Platforms, and Translational Pathways2025