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April 12, 2026The American Surgeon

Photodynamic Therapy as an Adjunct During Stent-Bridged Neoadjuvant Management of Obstructive Colon Cancer: A Case-Based Narrative Review

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Authors

BLBimin LiuZMZhen MaZWZhuanfang Wang

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Overview

Narrative review explores photodynamic therapy's role as an adjunct in obstructive colon cancer, suggesting its potential alongside standard treatments.

Key Points

  • To investigate the use of photodynamic therapy as an adjunct in managing obstructive left-sided colon cancer using a case study approach.
  • Presented a case of obstructive rectosigmoid adenocarcinoma managed with SEMS placement, PDT, and neoadjuvant systemic therapy.
  • Reviewed management pathways for obstructing left-sided colon cancer including emergency surgery and SEMS.
  • Summarized evidence and guidelines on SEMS and neoadjuvant therapy for colon cancer.
  • The case showed that PDT is technically feasible in conjunction with SEMS and systemic therapy.
  • Pathologic complete response was achieved after combining PDT with standard treatment measures.
  • While the findings are promising, they do not establish efficacy and call for further prospective studies.

Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/69db38534fe01fead37c6986https://doi.org/10.1177/00031348261441681
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Management of Malignant Left-Side Colonic Obstruction Using Self-Expandable Metal Stents as a Bridge to Elective Surgery: A Case Report and Literature Review2025
  2. 2A Novel Approach in Colon Cancer Treatment Successful Conversion of Locally Advanced Colon Cancer Using Endoscopic Rendezvous Technique Combined with Multimodal Therapy—A Case Report and Literature Review2025
  3. 3Case report: A clinical report of photodynamic neoadjuvant combined with fluorescent laparoscopic localization robotic surgery for the treatment of patients with advanced colorectal cancer combined with obstruction2024 · 1 citations
  4. 4Role of a Preoperative Completion Colonoscopy in Patients With Obstructed Colorectal Cancer Post Self‐Expandable Metallic Stent ( <scp>SEMS</scp> ) Placement as a Bridge to Surgery ( <scp>BTS</scp> )2026
  5. 5Colonic Stenting as a Bridge to Surgery Versus Emergency Resection in Left-Sided Malignant Large Bowel Obstruction: A Systematic Review2026