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August 12, 2025Photodiagnosis and Photodynamic TherapyOpen Access

A Novel Approach in Colon Cancer Treatment Successful Conversion of Locally Advanced Colon Cancer Using Endoscopic Rendezvous Technique Combined with Multimodal Therapy—A Case Report and Literature Review

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Authors

WPWeigao PuBXBo XuYWYunpeng Wang

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Overview

Case report highlights successful conversion surgery in a young woman with treatment-refractory locally advanced colon cancer, suggesting the efficacy of innovative therapies.

Key Points

  • Successful endoscopic photodynamic therapy downstaged locally advanced colon cancer, enabling surgery.
  • The patient showed partial tumor response after treatment, including neoadjuvant therapy and immunotherapy.
  • Analysis of the case used a combined approach of endoscopic PDT and dual-route therapy for better outcomes.
  • The findings emphasize the potential for improved bowel function restoration in challenging colon cancer cases.

Cite This Study

Pu et al. (2025) studied this question.

synapsesocial.com/papers/68a360f20a429f7973329b91https://doi.org/10.1016/j.pdpdt.2025.104761
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Case report: A clinical report of photodynamic neoadjuvant combined with fluorescent laparoscopic localization robotic surgery for the treatment of patients with advanced colorectal cancer combined with obstruction2024 · 1 citations
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  3. 3Role of neoadjuvant therapies in locally advanced colon cancer2025 · 6 citations
  4. 4Neoadjuvant short-course radiotherapy combined with CAPOX and PD-1 inhibitor for MSS/pMMR high-risk locally advanced colon cancer: A randomized, prospective, multicentre, phase II trial (TORCH-C).2026
  5. 5Curative Surgery After Neoadjuvant Chemotherapy for Locally Advanced Sigmoid Colon Cancer With Extensive Abdominal Wall Invasion: A Case Report2024