Why the study?
Are distinct plasma metabolomic profiles associated with RV dilation, mortality, and disease severity in patients with Pulmonary Arterial Hypertension?
Are distinct plasma metabolomic profiles associated with RV dilation, mortality, and disease severity in patients with Pulmonary Arterial Hypertension?
Answers are grounded in this paper and cite their sources.
Polyamine, histidine, and sphingomyelin metabolic pathways represent promising biomarker candidates for identifying PAH patients at high risk for poor outcomes such as RV dilation and mortality.
Distinct plasma metabolomic profiles are associated with RV dilation, mortality, and measures of disease severity in PAH. Polyamine, histidine, and sphingomyelin metabolic pathways represent promising candidates for identifying patients at high risk for poor outcomes and investigation into their roles as markers or mediators of disease progression and RV adaptation.
No takes yet. Share an insight, caveat, or question.
Pi et al. (2023) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: