Population
Isolated perfused rat liver model, using small chylomicrons from mesenteric lymph of estradiol-treated rats…
Comparison
Addition of C apolipoproteins and rat… vs No addition of C apolipoproteins
Design
Preclinical
Authors
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May regulate remnant clearance in rodents; leaves open translation to human dyslipidemia or therapies.
C apolipoproteins inhibit the premature hepatic uptake of newly secreted chylomicrons and VLDL, suggesting that depletion of these apolipoproteins is required to facilitate remnant hepatic uptake.
Windler et al. (1985) studied this question.
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