Key result
Many individuals have remnant very low density lipoproteins in their plasma, but the beta-migrating remnant in primary dysbetalipoproteinemia contains structurally abnormal arginine-rich protein.
Cross-Sectional
Identifies structural abnormalities in the arginine-rich apoprotein of VLDL remnants in patients with primary dysbetalipoproteinemia.
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May indicate distinct pathogenesis in primary dysbetalipoproteinemia; leaves open whether arginine-rich protein defects drive remnant accumulation more broadly.
Pagnan et al. (1977) conducted a cross-sectional in Hyperlipidemia and primary dysbetalipoproteinemia. Very low density lipoproteins (VLDL) with fast and slow pre-beta electrophoretic mobility was evaluated on Chemical composition and electrophoretic mobility of VLDL populations. Many individuals have remnant very low density lipoproteins in their plasma, but the beta-migrating remnant in primary dysbetalipoproteinemia contains structurally abnormal arginine-rich protein.
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