Why the study?
Does implantation of a cardioverter-defibrillator reduce sudden death from arrhythmia in patients with severe, nonischemic dilated cardiomyopathy treated with ACE inhibitors and beta-blockers?
Does implantation of a cardioverter-defibrillator reduce sudden death from arrhythmia in patients with severe, nonischemic dilated cardiomyopathy treated with ACE inhibitors and beta-blockers?
Prophylactic ICD implantation significantly reduces sudden arrhythmic death in patients with severe nonischemic dilated cardiomyopathy on optimal medical therapy.
May support ICD consideration for arrhythmic protection in nonischemic cardiomyopathy; leaves open all-cause mortality impact pending further study.
In patients with severe, nonischemic dilated cardiomyopathy who were treated with ACE inhibitors and beta-blockers, the implantation of a cardioverter-defibrillator significantly reduced the risk of sudden death from arrhythmia and was associated with a nonsignificant reduction in the risk of death from any cause.
No takes yet. Share an insight, caveat, or question.
Kadish et al. (2004) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: