Does greater LVMI and LV concentric hypertrophy increase the risk of adverse incident CVD events in adults free of prevalent CVD?
Increased left ventricular mass index and concentric hypertrophy identified by CMR in asymptomatic adults strongly predict future cardiovascular events, suggesting a potential target for primary prevention.
Among adults free of prevalent CVD in the community, greater LVMI and LV concentric hypertrophy are associated with a marked increase in adverse incident CVD events. The potential benefit of aggressive primary prevention to modify LV mass and geometry in these adults requires further investigation.
Tsao et al. (2015) studied this question.