March 17, 2020Journal of Internal Medicine196 citationsOpen Access
View Full PaperContribution of remnant cholesterol to cardiovascular risk
Structured PICO
Does lower remnant cholesterol reduce recurrent MACE in individuals with a diagnosis of myocardial infarction or ischaemic stroke?
P
Population
Individuals with a diagnosis of myocardial infarction or ischaemic stroke
I
Intervention
Lower remnant cholesterol of 0.8 mmol L-1 (32 mg dL-1)
O
Outcome
Recurrent MACEcomposite
Lowering remnant cholesterol may significantly reduce recurrent MACE in secondary prevention for patients with prior MI or ischemic stroke.
Abstract
In individuals with a diagnosis of myocardial infarction/ischaemic stroke, a lower remnant cholesterol of 0.8 mmol L-1 (32 mg dL-1 ) was estimated to reduce recurrent MACE by 20% in secondary prevention. Our data indicate an unmet medical need for secondary prevention in individuals with high nonfasting remnant cholesterol levels.