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Accounting for cellular heterogeneity is critical in epigenome-wide association studies | Synapse

February 4, 2014Open Access

Accounting for cellular heterogeneity is critical in epigenome-wide association studies

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Our findings underscore the importance of considering cell composition variability in epigenetic studies based on whole blood and other heterogeneous tissue sources. We also provide software for estimating and exploring this composition confounding for the Illumina 450k microarray.

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Cite This Study

Jaffe et al. (Tue,) studied this question.

synapsesocial.com/papers/69dbd29c7d378569a9836159 https://doi.org/https://doi.org/10.1186/gb-2014-15-2-r31