What question did this study set out to answer?

To assess the frequency, clinical features, and clinical significance of ictal central apnea during epileptic seizures.

January 16, 2018EpilepsiaOpen Access

The incidence and significance of periictal apnea in epileptic seizures

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Clinical review demonstrates frequent ictal central apnea in focal epilepsy, suggesting prolonged episodes serve as potential SUDEP biomarkers.

To assess the frequency, clinical features, and clinical significance of ictal central apnea during epileptic seizures.
Evaluated respiratory and polygraphic measurements alongside electroencephalography (EEG) during focal epileptic seizures.
Analyzed the timing, duration, and semiological patterns of ictal central apnea across temporal and extratemporal seizure onsets.
Ictal central apnea (ICA) occurs frequently as a self-limiting feature of focal seizures, manifesting more often in temporal than extratemporal epilepsy, and commonly starts before surface EEG onset.
Prolonged ICA (≥60 seconds) correlates with severe hypoxemia and represents a potential biomarker for sudden unexpected death in epilepsy (SUDEP).
Patients typically present with ICA agnosia and unawareness, meaning episodes often remain unrecognized without polygraphic respiratory monitoring.

Lacuey et al. (2018) studied this question.

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Clinical review demonstrates frequent ictal central apnea in focal epilepsy, suggesting prolonged episodes serve as potential SUDEP biomarkers.