Why the study?
Does hemodynamics play a distinct role in the development of aortopathy in patients with bicuspid aortic valve?
Does hemodynamics play a distinct role in the development of aortopathy in patients with bicuspid aortic valve?
Hemodynamics do not appear to have a distinct role in the overall development of bicuspid aortopathy, despite localized intimal and medial alterations.
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Does not support hemodynamics-driven aortopathy in BAV; leaves open intrinsic wall factors for prospective study.
In our study population, we could not demonstrate a potential distinct role for hemodynamics in the development of aortopathy in BAV patients even if corrected for aortic diameter, raphe position, or whether the valve is stenotic or regurgitant. The intimal layer and inner media however showed alterations in all jet specimens.
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Grewal et al. (2019) studied this question.
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