Why the study?
Does longitudinal evaluation of Heart Rate Variability (HRV) predict symptomatic or inflammatory flare in patients with Ulcerative Colitis (UC)?
Does longitudinal evaluation of Heart Rate Variability (HRV) predict symptomatic or inflammatory flare in patients with Ulcerative Colitis (UC)?
Longitudinal monitoring of heart rate variability may serve as a predictive biomarker for impending symptomatic or inflammatory flares in patients with ulcerative colitis.
Hypothesis-generating for HRV monitoring to predict UC flares; prospective trials needed before clinical adoption.
Longitudinally evaluated HRV was associated with UC symptoms, inflammation, and perceived and physiological measures of stress. Significant changes in HRV were observed before the development of symptomatic or inflammatory flare.
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Hirten et al. (2020) studied this question.
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