PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
October 26, 2022Journal of Clinical Oncology114 citationsOpen Access

Alliance A071401: Phase II Trial of Focal Adhesion Kinase Inhibition in Meningiomas With Somatic NF2 Mutations

View Full Paper
PBPriscilla K. BrastianosETErin TwohyEGElizabeth R. Gerstner

Key Points

Key points are not available for this paper at this time.

Abstract

GSK2256098 was well tolerated and resulted in an improved PFS6 rate in patients with recurrent or progressive NF2-mutated meningiomas, compared with historical controls. The criteria for promising activity were met, and FAK inhibition warrants further evaluation for this patient population.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Brastianos et al. (2022) studied this question.

synapsesocial.com/papers/69dc6a20f5368a34db359204https://doi.org/10.1200/jco.21.02371
Ask AI
Helpful
Bookmark
Share
View Full Paper