Potential Mortality Reduction With Optimal Implementation of Angiotensin Receptor Neprilysin Inhibitor Therapy in Heart Failure
Why the study?
Does optimal implementation of ARNI therapy prevent deaths in patients with HFrEF?
Population
Patients with heart failure with reduced ejection fraction (HFrEF)
Design
Other
Authors
Discussion
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Member takes
Implication
May support wider ARNI uptake in HFrEF to avert deaths; leaves open prospective confirmation of population impact.
Structured PICO
Does optimal implementation of ARNI therapy prevent deaths in patients with HFrEF?
P
Population
Patients with heart failure with reduced ejection fraction (HFrEF)
I
Intervention
Optimal implementation of Angiotensin Receptor Neprilysin Inhibitor (ARNI) therapy
O
Outcome
Deaths prevented (mortality reduction)hard clinical
Timely and optimal implementation of ARNI therapy could have a material impact on population health by preventing deaths among patients with HFrEF.
Cite This Study
Fonarow et al. (2016) studied this question.