Clinical cohort study shows a 33% five-year survival following rescue surgery for downstaged colorectal liver metastases, highlighting curative viability despite frequent disease recurrence.
Modern chemotherapy allows 12.5% of patients with unresectable CRLM to be rescued by liver surgery. Despite a high rate of recurrence, 5-year survival is 33% overall, with a wide use of repeat hepatectomies and extrahepatic resections. Four preoperative risk factors could select the patients most likely to benefit from this strategy.
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Adam et al. (2004) studied this question.
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