Key result
Stent-based pulmonary angioplasty for PPAS shows a ~46% 3-year ISR risk despite high long-term survival.
Why the study?
Isolated peripheral pulmonary artery stenosis lacks standardized therapeutic strategies, and the long-term durability and incidence and determinants of in-stent restenosis after stent implantation remain unclear.
Does stent-based pulmonary angioplasty improve hemodynamics, functional capacity, and long-term survival in adults with isolated peripheral pulmonary artery stenosis?
Cohort (n=23)
No
Does stent-based pulmonary angioplasty improve hemodynamics, functional capacity, and long-term survival in adults with isolated peripheral pulmonary artery stenosis?
Stent-based angioplasty for isolated peripheral pulmonary artery stenosis provides excellent long-term survival and hemodynamic improvement, though frequent in-stent restenosis necessitates structured surveillance and reintervention.
Requires structured surveillance and reintervention after stent-based angioplasty; extends evidence of sustained hemodynamic, functional, and survival benefits in isolated peripheral pulmonary artery stenosis.
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Kanezawa et al. (2026) conducted a cohort in Isolated peripheral pulmonary artery stenosis (PPAS) (n=23). Stent-based pulmonary angioplasty was evaluated on 3-year cumulative incidence of in-stent restenosis (ISR). Stent-based pulmonary angioplasty for isolated PPAS had a 45.8% 3-year incidence of in-stent restenosis, but estimated 5- and 10-year survival rates were 90.4% and 80.4%.
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