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Findings reveal low-dose polystyrene nanoplastics activate AMPK for liver protection in high-fat diet conditions, suggesting health implications of microplastics.
Our results indicate low-dose PS-NPs can activate the AMPK pathway and lipophagy, thereby alleviating liver injury through a stress adaptation response under high-fat diet conditions. Our findings elucidate the context-dependent interaction between microplastics and dietary patterns in liver diseases development and provide novel insights into the health effects of microplastics.
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Luo et al. (2026) studied this question.
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