What question did this study set out to answer?

Examine the design and therapeutic application of small hybrid heteroaromatic compounds engineered to modulate multiple cancer pathways simultaneously.

January 1, 2017RSC AdvancesOpen Access

Small hybrid heteroaromatics: resourceful biological tools in cancer research

View Full Paper

Ask AI

Bookmark

Authors

VAVikrant AbbotGraphic Era University PSPoonam SharmaJaypee University of Information Technology SDSaurabh Sudha DhimanSouth Dakota School of Mines and Technology

Discussion

Member takes

Implication

Review reveals multi-target modulation by hybrid heteroaromatics in complex diseases, indicating opportunities to reduce side effects seen with single-target cancer therapies.

Key Points

Examine the design and therapeutic application of small hybrid heteroaromatic compounds engineered to modulate multiple cancer pathways simultaneously.
Conceptual evaluation of hybrid drug design strategies combining two or more distinct, covalently linked pharmacophores.
Assessment of multitarget drug mechanisms designed to counteract off-target toxicities and treatment resistance in complex diseases.
Conjugation of multiple active heteroaromatic units enables concurrent disruption of distinct biological targets in cancer models.
Dual-acting hybrid frameworks demonstrate potential to lower required clinical dosages and lessen adverse events linked to conventional single-agent regimens.

Cite This Study

Abbot et al. (2017) studied this question.

synapsesocial.com/papers/69dc9f2d89c4deb67d3593a9 https://doi.org/10.1039/c6ra24662a

View Full Paper

Ask AI

Bookmark

Implication

Review reveals multi-target modulation by hybrid heteroaromatics in complex diseases, indicating opportunities to reduce side effects seen with single-target cancer therapies.

Small hybrid heteroaromatics: resourceful biological tools in cancer research

Discussion

Member takes

Implication

Key Points

Cite This Study

Small hybrid heteroaromatics: resourceful biological tools in cancer research

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider