Why the study?
Does tight perioperative blood glucose control reduce postoperative renal impairment and failure in non-diabetic patients undergoing cardiac surgery?
Does tight perioperative blood glucose control reduce postoperative renal impairment and failure in non-diabetic patients undergoing cardiac surgery?
Tight perioperative glucose control in non-diabetic cardiac surgery patients is associated with reduced renal impairment, need for dialysis, and 30-day mortality.
May support tighter perioperative glucose targets in non-diabetic cardiac surgery; leaves open confirmation by RCTs before practice change.
In non-diabetic patients, tight perioperative blood glucose control is associated with a significant reduction in postoperative renal impairment and failure after cardiac surgery according to the RIFLE criteria. In non-diabetics, tight blood glucose control was associated with a decreased need for postoperative dialysis, as well as 30-day mortality, despite of a relatively short ICU stay.
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Lecomte et al. (2008) studied this question.
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