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June 10, 2002Archives of Internal Medicine

Relative Impact of Risk Factors for Deep Vein Thrombosis and Pulmonary Embolism

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Why the study?

What is the population attributable risk of various risk factors for deep vein thrombosis and pulmonary embolism?

Population

625 residents with a definite first lifetime deep vein thrombosis or pulmonary embolism diagnosed during the…

Design

Case-control

Follow-up

15-year period (1976 to 1990)

Authors

John A. Heit
John A. HeitVascular Medicine
WOW. Michael O’FallonFundación Juan MarchTPTanya M. PettersonVascular Medicine

Discussion

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Overview

Institutionalized patients may drive most community VTE; leaves open whether prophylaxis reduces incidence in prospective studies.

Structured PICO

What is the population attributable risk of various risk factors for deep vein thrombosis and pulmonary embolism?

P
Population
625 residents with a definite first lifetime deep vein thrombosis or pulmonary embolism diagnosed during the 15-year period 1976 to 1990 and 625 unaffected residents matched for age and sex (total n=1250)
C
Comparator
Unaffected residents matched for age and sex
O
Outcome
Population attributable risk for deep vein thrombosis and pulmonary embolism associated with venous thromboembolism risk factorshard clinical

Institutionalization and related factors account for over 50% of all VTE cases in the community, highlighting the critical need for prophylaxis in hospitalized medical patients.

Cite This Study

Heit et al. (2002) studied this question.

synapsesocial.com/papers/69dd13dc0de68e8319e53dfehttps://doi.org/10.1001/archinte.162.11.1245
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cost of Long-Term Complications of Deep Venous Thrombosis of the Lower Extremities: An Analysis of a Defined Patient Population in Sweden1997 · 253 citations
  2. 2Physician Practices in the Prevention of Venous Thromboembolism1991 · 220 citations
  3. 3ESTIMATING THE POPULATION ATTRIBUTABLE RISK FOR MULTIPLE RISK FACTORS USING CASE-CONTROL DATA1985 · 1,249 citations
  4. 4The Long-Term Clinical Course of Acute Deep Venous Thrombosis1996 · 2,116 citations
  5. 5Risk Factors for Deep Vein Thrombosis and Pulmonary Embolism2000 · 2,186 citations