Elevated Plasma Endothelin-1 Concentrations Are Associated with the Severity of Illness in Patients with Sepsis

40 individuals total: 11 septic patients (studied during the first 24 hours after development of sepsis syndrome), 15 nonseptic postoperative patients (studied 24 hours after open heart surgery), and 14 healthy volunteers.

Nonseptic postoperative cardiac patients and healthy volunteers

Plasma immunoreactive endothelin-1 concentrations and their correlation with cardiac index, APACHE II score, and plasma creatinine levelssurrogate