What question did this study set out to answer?

Determine the incidence of symptomatic in-hospital deep vein thrombosis and pulmonary embolism in patients receiving standard thromboprophylaxis after hip or knee arthroplasty.

January 17, 2012JAMA

Symptomatic In-Hospital Deep Vein Thrombosis and Pulmonary Embolism Following Hip and Knee Arthroplasty Among Patients Receiving Recommended Prophylaxis

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Population

Patients undergoing total primary knee arthroplasty (TPKA) or total primary hip arthroplasty (TPHA)

Design

Cohort

Follow-up

prior to hospital discharge

Authors

JJJean‐Marie JanuelÉcole des Hautes Études en Santé Publique GCGuanmin ChenCleveland State University CRChristiane RuffieuxUniversity of Calgary

Discussion

Member takes

Implication

Early symptomatic VTE persists after arthroplasty despite prophylaxis; leaves open whether intensified regimens reduce events in routine care.

Key Points

Determine the incidence of symptomatic in-hospital deep vein thrombosis and pulmonary embolism in patients receiving standard thromboprophylaxis after hip or knee arthroplasty.
Assessed symptomatic venous thromboembolism occurrence prior to hospital discharge.
Evaluated patients undergoing total knee arthroplasty or total hip arthroplasty managed with guideline-recommended thromboprophylaxis.
Approximately 1 in 100 patients undergoing total knee arthroplasty developed symptomatic venous thromboembolism prior to discharge.
Approximately 1 in 200 patients undergoing total hip arthroplasty developed symptomatic venous thromboembolism prior to discharge.

Structured PICO

Population

Patients undergoing total primary knee arthroplasty (TPKA) or total primary hip arthroplasty (TPHA)

Intervention

Current recommended VTE prophylaxis

Outcome

Symptomatic in-hospital deep vein thrombosis and pulmonary embolism (symptomatic VTE) prior to hospital dischargehard clinical

Despite recommended prophylaxis, symptomatic VTE occurs in approximately 1% of knee and 0.5% of hip arthroplasty patients before hospital discharge.

Cite This Study

Januel et al. (2012) studied this question.

synapsesocial.com/papers/69dd46a67d97b7e86940c84b https://doi.org/10.1001/jama.2011.2029

Topics

Pulmonary embolism

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Implication

Early symptomatic VTE persists after arthroplasty despite prophylaxis; leaves open whether intensified regimens reduce events in routine care.

Symptomatic In-Hospital Deep Vein Thrombosis and Pulmonary Embolism Following Hip and Knee Arthroplasty Among Patients Receiving Recommended Prophylaxis

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Symptomatic In-Hospital Deep Vein Thrombosis and Pulmonary Embolism Following Hip and Knee Arthroplasty Among Patients Receiving Recommended Prophylaxis

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Topics

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