Does third-generation TAVI provide similar device success and complication rates in patients with extra-large aortic annulus compared to those with regular-sized annulus?
Third-generation TAVI is feasible and safe in patients with extra-large aortic annuli, though moderate paravalvular leak remains a clinical concern.
Treatment of ELA patients with third-generation TAVI prostheses is feasible and safe, providing similar device success and complication rates as in matched controls with regular-sized aortic annulus. Post-interventional pacemaker implantation rates were low compared to the control group, yet incidence of moderate PVL remains problematic in ELA patients.
Hof et al. (Mon,) studied this question.