Key result
Self-expandable TAVR is associated with ~65% more AR ≥grade 2 than balloon-expandable valves, predicting mortality.
Why the study?
Does the use of self-expandable versus balloon-expandable devices affect the incidence of postprocedural aortic regurgitation and 1-year mortality in patients undergoing TAVR?
Population
2,769 consecutive patients who underwent transcatheter aortic valve replacement and had postprocedural…
Comparison
Self-expandable transcatheter aortic valve… vs Balloon-expandable transcatheter aortic valve…
Design
Cohort
Follow-up
median 306 days (Q1-Q3=178-490)
Authors
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May warrant AR vigilance with self-expandable TAVR; leaves open randomized confirmation of device effects on mortality.
Observational (n=2,769)
Yes
Does the use of self-expandable versus balloon-expandable devices affect the incidence of postprocedural aortic regurgitation and 1-year mortality in patients undergoing TAVR?
Absolute Event Rate: 21.5% vs 13%
p-value: p=0.0001
Postprocedural aortic regurgitation ≥ grade 2 is more common with self-expandable TAVR devices compared to balloon-expandable devices and serves as a strong independent predictor of 1-year mortality.
Belle et al. (2014) conducted an observational in Transcatheter aortic valve replacement (TAVR) (n=2,769). Self-expandable TAVR vs. Balloon-expandable TAVR was evaluated on Postprocedural aortic regurgitation ≥grade 2 (p=0.0001). Postprocedural aortic regurgitation ≥grade 2 was more frequent with self-expandable than balloon-expandable TAVR (21.5% vs 13.0%; P=0.0001) and independently predicted 1-year mortality.
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