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March 12, 2011Heart

Aortic regurgitation after transcatheter aortic valve implantation: incidence and early outcome. Results from the German transcatheter aortic valve interventions registry

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Why the study?

Does significant aortic regurgitation after TAVI increase in-hospital mortality in patients with severe aortic stenosis?

Population

690 patients with severe aortic stenosis treated with TAVI, mean age 81.4±6.3 years, 44% men, mean logistic…

Comparison

Transcatheter aortic valve implantation… vs TAVI resulting in no or mild aortic regurgitation

Design

Cohort

Follow-up

in-hospital

Authors

MAMohamed Abdel‐WahabRZRalf ZahnMHMartin Horack

Discussion

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Member takes

Overview

Significant post-TAVI AR signals higher in-hospital mortality risk; hypothesis-generating in observational data and should not yet change practice.

Structured PICO

Does significant aortic regurgitation after TAVI increase in-hospital mortality in patients with severe aortic stenosis?

P
Population
690 patients with severe aortic stenosis treated with TAVI, mean age 81.4±6.3 years, 44% men, mean logistic Euroscore 20.4±13.1%, from the prospective multicentre German transcatheter aortic valve interventions registry.
I
Intervention
Transcatheter aortic valve implantation (TAVI) resulting in significant aortic regurgitation (AR ≥2/4)
C
Comparator
TAVI resulting in no or mild aortic regurgitation
O
Outcome
In-hospital deathhard clinical

Significant aortic regurgitation after TAVI is a common complication (17.2%) that independently predicts increased in-hospital mortality.

Cite This Study

Abdel‐Wahab et al. (2011) studied this question.

synapsesocial.com/papers/6a82b001aa66c98ddba0caadhttps://doi.org/10.1136/hrt.2010.217158
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Transcatheter aortic valve implantation: first results from a multi-centre real-world registry2010 · 599 citations
  2. 2Transcatheter Aortic Valve Implantation for the Treatment of Severe Symptomatic Aortic Stenosis in Patients at Very High or Prohibitive Surgical Risk2010 · 981 citations
  3. 3Percutaneous transarterial aortic valve implantation: what do we know?2010 · 153 citations
  4. 4Haemodynamic evaluation of aortic regurgitation after transcatheter aortic valve implantation using cardiovascular magnetic resonance2011 · 98 citations
  5. 5Transcatheter valve implantation for patients with aortic stenosis: a position statement from the European Association of Cardio-Thoracic Surgery (EACTS) and the European Society of Cardiology (ESC), in collaboration with the European Association of Percutaneous Cardiovascular Interventions (EAPCI)2008 · 310 citations