Why the study?
Small coronary artery atherosclerosis is associated with higher procedural complications and impaired outcomes, complicated by an unclear vessel definition and emerging treatment options.
This review provides an overview of the definition, interventional management (including drug-coated balloons vs. drug-eluting stents), and prognosis of small coronary artery atherosclerosis.
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Individualized device choice persists in small vessel CAD; leaves open dedicated RCTs comparing DCB and DES.
The issue of small coronary artery atherosclerosis represents an intriguing aspect of coronary artery disease, which is related with higher rates of peri- and post-procedural complications and impaired long-term outcome. This problem is further complicated by the unclear definition of small coronary vessel. Recent randomized controlled trials have provided new data on possible novel interventional treatment of small coronary vessels with drug-coated balloons instead of traditional new-generation drug-eluting stent implantation. Also, the conservative management represents a therapeutic option in light of the results of the recent ISCHEMIA trial. The current article provides an overview of the most appropriate definition, interventional management, and prognosis of small coronary artery atherosclerosis.
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Wybraniec et al. (2020) studied this question.
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