What question did this study set out to answer?

To evaluate the feasibility and performance of a dual aperture fluorescence ratio approach for the intraoperative identification of close surgical margins during oral squamous cell carcinoma resections.

January 17, 2024Journal of Biomedical OpticsOpen Access

Improved intraoperative identification of close margins in oral squamous cell carcinoma resections using a dual aperture fluorescence ratio approach: first in-human results

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To evaluate the feasibility and performance of a dual aperture fluorescence ratio approach for the intraoperative identification of close surgical margins during oral squamous cell carcinoma resections.
Conducted a first-in-human clinical evaluation utilizing a dual aperture fluorescence ratio (dAFR) imaging technique during oral squamous cell carcinoma resection procedures.
The dual aperture fluorescence ratio approach successfully enhanced intraoperative detection of close surgical margins compared to conventional visual assessment.

Implication

First-in-human study demonstrates improved detection of close surgical margins using dual aperture fluorescence ratios in oral cancer surgery, suggesting better intraoperative resection guidance.

Abstract

These results provide evidence that the dAFR approach potentially improves detection of close surgical margins.

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Cite This Study

Rounds et al. (2024) studied this question.

synapsesocial.com/papers/69dd4e1ccaee84831440c62a https://doi.org/10.1117/1.jbo.29.1.016003

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Implication

First-in-human study demonstrates improved detection of close surgical margins using dual aperture fluorescence ratios in oral cancer surgery, suggesting better intraoperative resection guidance.

Abstract

These results provide evidence that the dAFR approach potentially improves detection of close surgical margins.

Improved intraoperative identification of close margins in oral squamous cell carcinoma resections using a dual aperture fluorescence ratio approach: first in-human results

Key Points

Implication

Abstract

Discussion

Cite This Study

Improved intraoperative identification of close margins in oral squamous cell carcinoma resections using a dual aperture fluorescence ratio approach: first in-human results

Key Points

Implication

Abstract

Discussion

Cite This Study

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