November 16, 2020New England Journal of Medicine637 citationsOpen Access
View Full PaperCryoballoon Ablation as Initial Therapy for Atrial Fibrillation
Structured PICO
Does cryoballoon ablation as initial first-line therapy improve safety and efficacy in patients with symptomatic paroxysmal atrial fibrillation?
P
Population
Patients with symptomatic paroxysmal atrial fibrillation
I
Intervention
Cryoballoon ablation as initial first-line therapy
Abstract
In patients with symptomatic paroxysmal atrial fibrillation that has not responded to medication, catheter ablation is more effective than antiarrhythmic drug therapy for maintaining sinus rhythm. However, the safety and efficacy of cryoballoon ablation as initial first-line therapy have not been established.