March 25, 2010Epidemiology and InfectionOpen Access

Low diversity of foot-and-mouth disease serotype C virus in Kenya: evidence for probable vaccine strain re-introductions in the field

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Population

8 foot-and-mouth disease (FMD) serotype C virus isolates from Kenya collected between 1967 and 2004

Design

Preclinical

Authors

ASAbraham SangulaProject Directorate on Foot and Mouth Disease HSHans R. SiegismundUniversity of Copenhagen GBGraham J. BelshamStatens Serum Institut

Discussion

Member takes

Implication

May indicate FMD vaccine re-introductions in Kenya; leaves open need for prospective validation before surveillance changes.

Structured PICO

Population

8 foot-and-mouth disease (FMD) serotype C virus isolates from Kenya collected between 1967 and 2004

Intervention

Analysis of nucleotide sequences encoding the capsid protein VP1

Outcome

Patterns of sequence divergence and evolution

The very low nucleotide diversity in FMD serotype C virus isolates from Kenya over 40 years suggests probable re-introductions of the vaccine strain into the field.

Cite This Study

Sangula et al. (2010) studied this question.

synapsesocial.com/papers/69dd595980eea7d3f699baa4 https://doi.org/10.1017/s0950268810000580

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March 25, 2010Epidemiology and InfectionOpen Access

Low diversity of foot-and-mouth disease serotype C virus in Kenya: evidence for probable vaccine strain re-introductions in the field

View Full Paper

Ask AI

Bookmark

Population

8 foot-and-mouth disease (FMD) serotype C virus isolates from Kenya collected between 1967 and 2004

Design

Preclinical

Authors

ASAbraham SangulaProject Directorate on Foot and Mouth Disease HSHans R. SiegismundUniversity of Copenhagen GBGraham J. BelshamStatens Serum Institut

Discussion

Member takes

Implication

May indicate FMD vaccine re-introductions in Kenya; leaves open need for prospective validation before surveillance changes.

Structured PICO

Population

8 foot-and-mouth disease (FMD) serotype C virus isolates from Kenya collected between 1967 and 2004

Intervention

Analysis of nucleotide sequences encoding the capsid protein VP1

Outcome

Patterns of sequence divergence and evolution

The very low nucleotide diversity in FMD serotype C virus isolates from Kenya over 40 years suggests probable re-introductions of the vaccine strain into the field.

Cite This Study

Sangula et al. (2010) studied this question.

synapsesocial.com/papers/69dd595980eea7d3f699baa4 https://doi.org/10.1017/s0950268810000580

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

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