Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 1, 1987Journal of VirologyOpen Access

Subtyping of European foot-and-mouth disease virus strains by nucleotide sequence determination

View Full Paper
Ask AI
Bookmark
Share

Population

Foot-and-mouth disease virus strains from 18 recent European outbreaks and 9 strains isolated more than 20…

Design

Preclinical

Authors

EBEwald BeckKSKarl G. Strohmaier

Discussion

Loading...

Member takes

Overview

Sequence analysis traces most FMD outbreaks to vaccine strains; supports its diagnostic utility but leaves open vaccine safety implications in livestock.

Structured PICO

P
Population
Foot-and-mouth disease virus strains from 18 recent European outbreaks and 9 strains isolated more than 20 years ago (total n=27)
I
Intervention
Nucleotide sequence determination (direct cDNA sequencing) of the VP1-coding regions
O
Outcome
Genetic relationship between outbreak viruses and vaccine strains

Nucleotide sequence analysis reveals that most recent European foot-and-mouth disease outbreaks were caused by vaccine strains, highlighting its utility as a standard diagnostic method.

Cite This Study

Beck et al. (1987) studied this question.

synapsesocial.com/papers/6a6f5703f44fa9f079dcc3a3https://doi.org/10.1128/jvi.61.5.1621-1629.1987
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison of the major antigenic determinants of different serotypes of foot-and-mouth disease virus1983 · 71 citations
  2. 2Sequence variation in the gene for the immunogenic capsid protein VP1 of foot-and-mouth disease virus type A.1985 · 66 citations
  3. 3Comparison of the amino acid sequence of the major immunogen from three serotypes of foot and mouth disease virus1982 · 87 citations
  4. 4Nucleotide sequence and corresponding amino acid sequence of the gene for the major antigen of foot and mouth disease virus1981 · 89 citations
  5. 5Location and Characterization of the Antigenic Portion of the FMDV Immunizing Protein1982 · 367 citations