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June 11, 2020Current Computer - Aided Drug Design

Elaboration of Novel TTK1 Inhibitory Leads via QSAR-Guided Selection of Crystallographic Pharmacophores Followed By In Vitro Assay

Mahmoud A. Al-Sha’er Mutasem O. Taha

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Abstract

Five hits confirmed significant TTK1 inhibitory profiles with IC50 values ranging between 11.7 and 76.6 mM.

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Al-Sha’er et al. (2020) studied this question.

synapsesocial.com/papers/69dd68470644c7b49d40d684 https://doi.org/10.2174/1573409916666200611122736

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